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We'd like to understand how you use our websites in order to improve them. Register your interest. They relate a case of a patient presenting a perineal lesion two years after the excision of a tumor caused by P. They comment on Mackinnon's pathogenic theory of South American Blastomycosis that presumes that lungs are the portal of entry of P.

Thus, mucocutaneous lesions are secondary to a primary pulmonary localization by hematogenous route. This is a preview of subscription content, log in to check access. Rent this article via DeepDyve. Balabanov, K. Google Scholar.

Campos, E. Micose de Lutz Blastomicose Sulamericana. Rio Grande do Sul. Blastomicose anal primitiva. Carneiro, J. Conti-Diaz, I. Montevideo 44 : — Fialho, A. Patogenia da Blastomicose Pulmonar. Fialho, F. Lacaz, C. Hospital R. Janeiro 39 : — Janeiro 33 : — Lima, F. Machado Fo, J. Janeiro 58 : 99— Mackinnon, J. Pathogenesis of South American Blastomycosis.

Blastomicosis Sudamericana experimental evolutiva por via pulmonar. An Fac. Miositis en la Blastomicosis Sudamericana y en la Histoplasmosis. Monteiro, A. Blastomicose perineo-anoretal. Janeiro 17 : — Oliveira, E. Blastomicose do reto. Sadek, H. Blastomicose perineal Arq. Veronesi, R. Blastomicose retal primitiva. Paulo 9 : — Yarzabal, L. Rectitis y lesiones perianales en la Blastomicosis Sudamericana experimental. Download references. Reprints and Permissions.

Londero, A. Mycopathologia et Mycologia Applicata 32, — Download citation. Issue Date : September Search SpringerLink Search. Immediate online access to all issues from Subscription will auto renew annually. References Balabanov, K.

Londero View author publications. You can also search for this author in PubMed Google Scholar. View author publications. Rights and permissions Reprints and Permissions. About this article Cite this article Londero, A.


Experimental Paracoccidioidomycosis in Mice

We'd like to understand how you use our websites in order to improve them. Register your interest. Three new Uruguayan paracoccidioidomycosis human cases are presented. Two of them correspond to the disseminated form with metastatic lesions at the oral mucosa; the remaining one, with important pulmonary bilateral lesions corresponds to the pure chronic pulmonary form of the disease which is recognized by the first time in the country. No doubt, these clinical forms will be found much more frequently in the endemic areas of Latin America if serological surveys are developed in the near future.


[Paracoccidioidomycosis: apropos of 3 new Uruguayan cases].

Virulence and infectivity of nine strains of Paracoccidioides brasiliensis were investigated in groups of mice which were inoculated intranasally or intravenously, and some of each were treated with corticosteroids. Fatal infections were not often seen among untreated mice, but mortality usually occurred when corticosteroids were given, regardless of the route of fungus inoculation. Prior treatment did not uniformly increase the incidence of infection, however; only in the case of intranasally inoculated mice was this effect seen. Most strains appeared to be more virulent when administered intravenously, with the exception of a single strain which, under the influence of corticosteroids, repeatedly displayed greatest virulence when given intranasally. All animals that died early in the course of the disease, irrespective of route of inoculation, always had acute pulmonary lesions and usually no other organ was involved.

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