ENDOCRINOLOGIA CLINICA VILAR PDF

The magnitude of prolactin PRL elevation can be useful in determining the etiology of hyperprolactinemia. However, exceptions to these rules are not rare. On the other hand, among patients with macroprolactinomas MACs , artificially low PRL levels may result from the so-called "hook effect". The screening for macroprolactin is mostly indicated for asymptomatic patients and those with apparent idiopathic hyperprolactinemia.

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Scientific Research An Academic Publisher. Vilar, L. ABSTRACT: Dunnigan-type partial lipodystrophy, which is characterized by a number of metabolic alterations, change in body fat distribution, and autosomal dominant inheritance pattern, is rare in the general population. Objective: To report the case of an adolescent with clinical and laboratory findings suggestive of Dunnigan-type partial lipodystrophy.

Methods: Case report and literature review. Results: A year-old adolescent presented at the clinic complaining of darkening of skin folds on her trunk and back. During physical examination, the presence of serious acanthosis nigricans in her cervical region, axillae, and intergluteal space was noted. Hirsutism in androgen-dependent areas was also observed, as well as relevant reduction of subcutaneous adipose tissue in the limbs, gluteal region, abdomen, and trunk and fat accumulation in the face and chin.

Affected patients display marked insulin resistance and may consequently develop diabetes mellitus, acanthosis nigricans, hirsutism, and polycystic ovary syndrome.

Conclusion: This case report highlights the importance of suspecting Dunnigan-type familial partial lipodystrophy in clinical practice.

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Endocrinologia Clinica - Vilar 6 edicao

Alana flag Denunciar. Heterogeneous distribution of serum prolactin values in apparently healthy young women, and the effects of oral contraceptive medication. Fertil Steril. Macroprolactinemia in hyperprolactinemic infertile women. Hyperprolactinemia and sexual function in men. Horm Res. J Clin Endocrinol Metab.

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Endocrinologia ClĂ­nica

Scientific Research An Academic Publisher. Vilar, L. ABSTRACT: Dunnigan-type partial lipodystrophy, which is characterized by a number of metabolic alterations, change in body fat distribution, and autosomal dominant inheritance pattern, is rare in the general population. Objective: To report the case of an adolescent with clinical and laboratory findings suggestive of Dunnigan-type partial lipodystrophy. Methods: Case report and literature review. Results: A year-old adolescent presented at the clinic complaining of darkening of skin folds on her trunk and back. During physical examination, the presence of serious acanthosis nigricans in her cervical region, axillae, and intergluteal space was noted.

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Endocrinologia Clinica - Vilar 6 edicao

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Endocrinologia Clinica Vilar Pdf

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