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No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. This book and the individual contributions contained in it are protected under copyright by the Publisher other than as may be noted herein.

Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein.

In using such information or methods, they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.

With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided i on procedures featured or ii by the manufacturer of each product to be administered to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.

Immunology and serology in laboratory medicine Rev. Includes bibliographical references and index. ISBN hardcover : alk. Turgeon, Mary Louise. Immunology and serology in laboratory medicine. Title: Immunology and serology in laboratory medicine. Immunologic Techniques—Laboratory Manuals. Immune System Diseases—immunology— Laboratory Manuals. Immune System Phenomena—Laboratory Manuals. Serology—methods—Laboratory Manuals.

QW ] Immunology and serology have come to represent the bedrock of laboratory diagnostics by underlying principles or practical applications.

The intention of this fifth edition of Immunology and Serology in Laboratory Medicine is to continue to fulfill the needs of medical laboratory technician MLT and medical laboratory science MLS students and their instructors for an entry-level text that encompasses the most current theory, practice, and clinical applications in the fields of immunology and serology. This textbook is written specifically for students and practitioners in clinical laboratory science.

Content delivery is competency-based to provide the framework for theory and practice, with a strong emphasis on clinical applications. Critical thinking is essential and has a renewed emphasis in this edition, with many more clinical case studies. Every chapter has applicable cases with extensively developed presentations, case-related multiple-choice questions, and critical analysis group discussion questions. These cases not only promote critical thinking and stimulate an overall interest in medicine, but highlight the essential role of the laboratory in patient diagnosis and treatment.

The organization of the book allows for tremendous flexibility in instructional design and delivery. The book is well suited for traditional on-campus instruction, hybrid or blended modes of teaching, and online delivery of courses. A new category of content is the emphasis on Internet-delivered references to sites for virtual laboratories and for the enhancement of learning the content presented in the book.

Students in the digital age are becoming more visual learners. Extensive use is made of new and highly acclaimed illustrations originally published in the New England Journal of Medicine, as well as classic presentations from highly regarded immunology reference books.

This adds a contemporary and exciting flair to a traditional college textbook. More tables and boxes have been added to chapters. Each chapter has the principle and clinical application of at least one related procedure. In some cases, this provides the requisite information for a course. The procedural protocol, including specimen collection, the required materials, actual procedure, and expected reference results, are published on the Evolve websites for students and instructors who wish to select that laboratory exercise in their curriculum.

Instructors can easily select procedures and create a customized laboratory manual that students can print, as needed. The benefits include reduction in the risk of soiling or contaminating their textbook in a wet laboratory.

By reducing the number of pages devoted to laboratory procedures in the text, which may not be desired in a course, the planet gets a little greener with associated savings in the cost of production.

The entire content of the book has been reviewed and updated with the newest technical and clinical information. Content of the book represents the basic knowledge required for certification examinations for MLT- and MLS-level graduates. Beyond basic knowledge and skills requirements, the text presents interdisciplinary topics and niche topics of transplantation and tumor immunology. Parts I and II provide foundational knowledge and skills that progress from basic immunologic mechanisms and serologic concepts to the theory of laboratory procedures, including molecular techniques.

In addition, they contain representative disorders of infectious and immunologic origin, as well as topics such as transplantation and tumor immunology. The sequence of the parts has been designed to accommodate the core needs of clinical laboratory students in basic concepts, the underlying theory of procedures, and immunologic manifestations of infectious diseases.

Because the needs of some students are more advanced in immunopathology, these topics are presented later in the text to allow students to analyze, evaluate abnormalities, and exercise critical thinking skills based on their knowledge of the preceding parts. Students may study specific components of the text, depending on the level, length, and objectives of the course. This fifth edition of Immunology and Serology in Laboratory Medicine capitalizes on the strengths of previous editions, beginning with the first edition in To address the needs of new learners, key terms and expanded glossary are featured in this edition.

These outlines should be of value to students in the organization of the material and may be of convenience to instructors in preparing lectures.

To streamline this text, the principles and clinical applications of representative procedures appear in every chapter of the text. The knowledge base in the field of immunology and serology continues to expand logarithmically.

Every chapter has been reviewed and analyzed by clinical laboratory science students and instructors and has been updated, as needed. Each chapter has at least one relevant case study and reference to at least one related procedure. Suggestions for web-based videos and virtual laboratories have been compiled by chapter and presented on the Evolve site. Representative procedures have been added. The chapter on molecular diagnostics see Chapter 14 continues to expand because of the increasing emphasis on this method of testing.

This chapter is unique and not available in competing textbooks. Representative case studies have been added to the chapters in this section. In addition, information related to tumor immunology has been revised. Although the content of immunology continues to expand, Immunology and Serology in Laboratory Medicine is written for clinical laboratory students in immunology who need an emphasis on the medical aspects of the discipline and the practical aspects of serology.

The fifth edition should provide students with a basic foundation in the theory and practice of clinical immunology and practical serology in a one- or twoterm course at MLT or MLS levels of instruction. The test bank can be used as review in class or for test development. More than of the questions in the instructor test bank are available for student use. The figures can be used during lectures to illustrate important concepts. The questions and answers are available to instructors.

Mary L. Turgeon Boston, Massachusetts St. Her career as an educator includes 15 years as a community college professor and program director and 14 years as an undergraduate and graduate university professor and administrator. Clinical Hematology has been translated into Spanish. Turgeon is the author of numerous professional journal articles.

Her consulting practice, Mary L. Turgeon and Associates www. Her professional involvement has offered her the opportunity to meet and collaborate with medical laboratory science colleagues in the United States and worldwide, including China, Italy, Japan, Qatar, Saudi Arabia, and the United Arab Emirates. Professional volunteer activities have taken her to Cambodia and Lesotho, Africa. Beginning about ad, the Chinese practiced a form of immunization by inhaling dried powders derived from the crusts of smallpox lesions.

When this practice became popular in England, it was discouraged at first, partly because the practice of inoculation occasionally killed or disfigured a patient.

Louis Pasteur is generally considered to be the Father of Immunology. Table lists some historic benchmarks in immunology. Immunology is defined as resistance to disease, specifically infectious disease. Immunology consists of the following: the study of the molecules, cells, organs, and systems responsible for the recognition and disposal of foreign nonself material; how body components respond and interact; the desirable and undesirable consequences of immune interactions; and the ways in which the immune system can be advantageously manipulated to protect against or treat disease Box Immunologists in the Western Hemisphere generally exclude from the study of immunology the relationship among cells during embryonic development.

The immune system is composed of a large complex set of widely distributed elements, with distinctive characteristics. Specificity and memory are characteristics of lymphocytes see Chapter 4. Various specific and nonspecific elements of the immune system demonstrate mobility, including T and B lymphocytes, immunoglobulins antibodies , complement, and hematopoietic cells.

This cooperative interaction involves specific cellular elements, cell products, and nonlymphoid elements. Cells of the immune system consist of lymphocytes, specialized cells that capture and display microbial antigen, and effector cells that eliminate microbes see Color Plate 1.

Such a system is necessary for survival. The distinction of self from nonself is made by an elaborate, specific recognition system. Specific cellular elements of the immune system include the lymphocytes. The immune system also has nonspecific effector mechanisms that usually amplify the specific functions. Nonspecific components of the immune system include mononuclear phagocytes, polymorphonuclear leukocytes, and soluble factors e.

Nonself substances range from life-threatening infectious microorganisms to a lifesaving organ transplantation.


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Immunology and Serology in Laboratory Medicine

Thank you for interesting in our services. We are a non-profit group that run this website to share documents. We need your help to maintenance this website. Please help us to share our service with your friends. Share Embed Donate. Turgeon and Associates Boston, Massachusetts; St. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher.

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