Sintomas gastrointestinais. Motilidade gastrointestinal. Foram investigados pacientes com Diabetes Mellitus, sendo 26 do tipo 1 e do tipo 2, e 50 pessoas aparentemente sadias, que integraram o grupo controle. METHODS: The frequencies of 13 digestive symptoms were determined in type 1 and type 2 diabetics and in 50 apparently healthy controls, utilizing a structured, standardized questionnaire. The frequencies of symptoms observed in Brazil were similar to those reported in studies from the North Hemisphere, a finding that does not support the hypothesis that external factors may influence the prevalence of gastrointestinal symptoms in diabetics. Diabetes mellitus.
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Mecanismos e fatores associados aos sintomas gastrointestinais em pacientes com diabetes melito. Foram selecionados os artigos mais atuais e representativos do tema. The most relevant and up-to-date articles on the topic were selected.
The complications caused by this disease in the digestive system, such as gastrointestinal symptoms nausea, vomiting, abdominal pain, heartburn, dysphagia, constipation, diarrhea, and fecal incontinence are well known.
The pathogenesis of changes in the gastrointestinal functions in patients with diabetes mellitus is still being investigated at the same time as the role of the enteric nervous system and its neurotransmitters has gained significance. As a consequence of the complications in the digestive system, which damage the enteric nervous system, patients with diabetes mellitus may have specific gastrointestinal motility disorders, some of which may be of great relevance, such as diabetic gastroparesis, constipation, and diarrhea.
Gastrointestinal dysfunction increases the morbidity of diabetes mellitus and worsens the quality of life of diabetic individuals. Diabetes mellitus affects the digestive system over the years. Because this condition worsens the quality of life of diabetic individuals and leads to complications, attention must be paid to gastrointestinal symptoms when treating patients with diabetes mellitus. Keywords: Diabetes mellitus, digestive signs and symptoms, gastrointestinal motility, etiology, child, adolescent.
A maioria dos estudos demonstra uma variedade de sintomas gastrointestinais em pacientes portadores do DM, embora muitos destes pacientes, particularmente os portadores do DMT1, possam apresentar-se sem sintomas gastrointestinais. Como a hiperglicemia causa sintomas gastrointestinais no DM? Destaca-se a metformina, do grupo das biguanidas, e as sulfonilureias.
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