Immune thrombocytopenia ITP is a disorder that can lead to easy or excessive bruising and bleeding. The bleeding results from unusually low levels of platelets — the cells that help blood clot. Formerly known as idiopathic thrombocytopenic purpura, ITP can cause purple bruises, as well as tiny reddish-purple dots that look like a rash. Children may develop ITP after a viral infection and usually recover fully without treatment. In adults, the disorder is often long term.
|Published (Last):||28 June 2014|
|PDF File Size:||8.31 Mb|
|ePub File Size:||5.63 Mb|
|Price:||Free* [*Free Regsitration Required]|
Immune thrombocytopenia ITP is a disorder that can lead to easy or excessive bruising and bleeding. The bleeding results from unusually low levels of platelets — the cells that help blood clot. Formerly known as idiopathic thrombocytopenic purpura, ITP can cause purple bruises, as well as tiny reddish-purple dots that look like a rash.
Children may develop ITP after a viral infection and usually recover fully without treatment. In adults, the disorder is often long term. If you don't have signs of bleeding and your platelet count isn't too low, you may not need any treatment. If your symptoms are more severe, treatment may include medications to boost your platelet count or surgery to remove your spleen.
Petechiae may look like a rash and usually appear in clusters. Here they appear on a leg A and on an abdomen B. Make an appointment with your doctor if you or your child develops warning signs that worry you. Bleeding that won't stop is a medical emergency. Seek immediate help if you or your child experiences bleeding that can't be controlled by the usual first-aid techniques, such as applying pressure to the area.
Immune thrombocytopenia usually happens when your immune system mistakenly attacks and destroys platelets, which are cell fragments that help blood clot. In adults, this may be triggered by infection with HIV , hepatitis or H.
In most children with ITP , the disorder follows a viral illness, such as the mumps or the flu. ITP is more common among young women. The risk appears to be higher in people who also have diseases such as rheumatoid arthritis, lupus and antiphospholipid syndrome.
If you're pregnant and your platelet count is very low or you have bleeding, you have a greater risk of heavy bleeding during delivery.
Your doctor may suggest treatment to maintain a stable platelet count, taking into account the effects on your baby. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. This content does not have an English version. This content does not have an Arabic version. Overview Immune thrombocytopenia ITP is a disorder that can lead to easy or excessive bruising and bleeding.
Petechiae Open pop-up dialog box Close. Petechiae Petechiae may look like a rash and usually appear in clusters. Request an Appointment at Mayo Clinic. ITP in children: How can I protect my child from complications?
Share on: Facebook Twitter. Show references Immune thrombocytopenia. National Heart, Lung, and Blood Institute. Accessed Feb. Ferri FF. Immune thrombocytopenic purpura. In: Ferri's Clinical Advisor Philadelphia, Pa. George JN, et al.
Immune thrombocytopenia ITP in adults: Clinical manifestations and diagnosis. Immune thrombocytopenia adult. Rochester, Minn. Immune thrombocytopenia ITP. Merck Manual Professional Version. Accessed March 12, Immune thrombocytopenia ITP in adults: Initial treatment and prognosis. Accessed March 13, Immune thrombocytopenia ITP in adults: Second-line and subsequent therapies.
Morrow ES Jr. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Show more related content. Mayo Clinic Marketplace Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
Immune thrombocytopenic purpura
ITP is reported in approximately 2 per , adults. ITP is more common in females of childbearing age and in pregnancy. In adults, the course is more chronic although spontaneous remission can also occur within months of initial diagnosis. A thorough and timely workup of thrombocytopenia is imperative to rule out other differentials of ITP as it is considered a diagnosis of exclusion. Primary care physicians encounter patients who exhibit signs of thrombocytopenia such as petechiae or purpura on a regular basis.
Idiopathic thrombocytopenic purpura
Universa Medicina warmly welcome the contributions from you about new basic and clinical including modern and epidemiological research on medicine and health. For Authors. Journal Statistics. View My Stats. Psaila B, Bussel T.
Idiopathic Thrombocytopenic Purpura (ITP)
This condition is now more commonly referred to as immune thrombocytopenia ITP. ITP can cause excessive bruising and bleeding. An unusually low level of platelets, or thrombocytes, in the blood results in ITP. Platelets are produced in the bone marrow. They help stop bleeding by clumping together to form a clot that seals cuts or small tears in blood vessel walls and tissues. Internal bleeding or bleeding on or under the skin can result.
Immune thrombocytopenia purpura ITP , also known as idiopathic thrombocytopenic purpura , is a type of thrombocytopenic purpura defined as an isolated low platelet count with a normal bone marrow in the absence of other causes of low platelets. Two distinct clinical syndromes manifest as an acute condition in children and a chronic condition in adults. The acute form often follows an infection and spontaneously resolves within two months. Chronic immune thrombocytopenia persists longer than six months with a specific cause being unknown. ITP is an autoimmune disease with antibodies detectable against several platelet surface structures.