They are common lesions and usually incidentally identified. Rathke pouch forms during the 4 th week of embryologic development as a rostral outpouching from the roof of the primitive oral cavity. The anterior wall of the pouch gives rise to the anterior lobe of the pituitary pars distalis. The posterior wall of the pouch does not proliferate and remains as the intermediate lobe of the pituitary pars intermedia.
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They are common lesions and usually incidentally identified. Rathke pouch forms during the 4 th week of embryologic development as a rostral outpouching from the roof of the primitive oral cavity.
The anterior wall of the pouch gives rise to the anterior lobe of the pituitary pars distalis. The posterior wall of the pouch does not proliferate and remains as the intermediate lobe of the pituitary pars intermedia.
The lumen of the pouch narrows to form a cleft Rathke cleft that normally regresses. Persistence of this cleft with the expansion is believed to be the origin of a Rathke cleft cyst. The wall of the cyst is typically lined by a single columnar cell layer of epithelium, often containing goblet cells, and is often ciliated. An intraluminal nodule which macroscopically appears white and is often adherent to the cyst wall although it may be free-floating is composed of solid tissue that represents desquamated cellular debris 3, On imaging, a Rathke cleft cyst is seen as a well defined non-enhancing midline cyst within the sella arising between the anterior and intermediate lobes of the pituitary.
Purely suprasellar location, although reported, is rare. On lateral skull x-ray, it can rarely cause sellar enlargement if reaches large size The signal characteristics vary according to the cyst composition, which may be mucoid or serous. When seen, it is hyperintense to surrounding fluid on T1 and hypointense on T2.
Depending on the signal of the surrounding fluid, it may be inapparent on one sequence or the other. Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Updating… Please wait. Unable to process the form. Check for errors and try again. Thank you for updating your details. Log In. Sign Up. Log in Sign up. Articles Cases Courses Quiz. About Blog Go ad-free. As of the latest update, Google Chrome and Microsoft Edge have made a breaking change to how file uploads are handled.
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Intracranial cysts: radiologic-pathologic correlation and imaging approach. Edit article Share article View revision history Report problem with Article.
URL of Article. Article information. System: Central Nervous System. Tag: pituitary. Synonyms or Alternate Spellings: Rathke's cleft cyst. Support Radiopaedia and see fewer ads. Cases and figures. Figure 1: histology Figure 1: histology. Case 1 Case 1.
Case 2 Case 2. Case 3 Case 3. Case 4 Case 4. Case 5 Case 5. Case 7 Case 7. Case 8: T2 hypointense cyst Case 8: T2 hypointense cyst.
Case 9 Case 9. Case 10 Case Case 11 Case Case 12 Case Case with fluid-fluid level Case with fluid-fluid level. Case 14 Case Case 15 Case Case growing Rathke cleft cyst Case growing Rathke cleft cyst. Case 17 Case Case with sellar enlargement Case with sellar enlargement. Imaging differential diagnosis. Teratoma Teratoma.
Arachnoid cyst Arachnoid cyst. Craniopharyngioma Craniopharyngioma. Cystic macroadenoma Cystic macroadenoma. Epidermoid cyst Epidermoid cyst. Loading more images Close Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Loading Stack - 0 images remaining. By System:. Patient Cases. Contact Us.
Bolsa de Rathke
Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed. Pituitary deficiency due to Rathke's cleft cysts is a rare, acquired pituitary hormone deficiency characterized by combination of headache, visual field defects that correlate with cyst size, and pituitary dysfunction.
In embryogenesis , Rathke's pouch is an evagination at the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary adenohypophysis , a part of the endocrine system. Rathke's pouch, and therefore the anterior pituitary, is derived from ectoderm. The pouch eventually loses its connection with the pharynx giving rise to the anterior pituitary. The anterior wall of Rathke's pouch proliferates, filling most of the pouch to form pars distalis and pars tuberalis. The posterior wall forms pars intermedia.
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