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Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: The emergence of whole genome sequencing WGS technologies as primary research tools has allowed for the detection of genetic diversity in Mycobacterium tuberculosis Mtb with unprecedented resolution.

WGS has been used to address a broad range of topics, including the dynamics of evolution, transmission and treatment. View on PubMed. Save to Library. Create Alert. Launch Research Feed. Share This Paper. Figures and Topics from this paper. Citations Publications citing this paper. Genetic diversity and dynamic distribution of Mycobacterium tuberculosis isolates causing pulmonary and extrapulmonary tuberculosis in Thailand. Correlation of drug resistance with Single Nucleotide Variations through genome analysis and experimental validation in a multi-drug resistant clinical isolate of M.

Dynamics of within-host Mycobacterium tuberculosis diversity and heteroresistance during treatment. Elucidation of drug resistance mutations in Mycobacterium tuberculosis isolates from North India by whole-genome sequencing. Renard Biology Haas , Bernhard Y.

Deciphering drug resistance in Mycobacterium tuberculosis using whole-genome sequencing: progress, promise, and challenges Keira A. Cohen , Abigail L. Earl Biology, Medicine Genome Medicine In-host population dynamics of M. Farhat Biology References Publications referenced by this paper. Comparative genomics of Esx genes from clinical isolates of Mycobacterium tuberculosis provides evidence for gene conversion and epitope variation. Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background.

Nigel J. Saunders , Urmi H. Blaxter Biology, Medicine The Journal of infection Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection Christopher B. Fortune Biology, Medicine Nature Genetics Whole-genome sequencing and social-network analysis of a tuberculosis outbreak. Jennifer L. Reed Biology, Medicine Journal of bacteriology Molecular tools for Mycobacterium tuberculosis genotyping. Juan C. Koup Biology, Medicine The Journal of experimental medicine Sacchettini Biology, Medicine PloS one Related Papers.

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Mycobacterium tuberculosis--heterogeneity revealed through whole genome sequencing.

Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. Corpus ID: Comparative molecular study of Mycobacterium tuberculosis strains, in times of antimicrobial drug resistance. Two of these strains: IH1 susceptible to isoniazid and IH2 resistant to isoniazid were recovered from cases of pulmonary tuberculosis which occurred in two brothers who lived together.


Efeitos adversos. Efeitos adversos menores. Efeitos adversos maiores. Categoria C. Efeitos adversos 3,4,5,7. Podem ser tratadas conforme o descrito para a isoniazida.



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